prevent the HIV virus envelope from fusing to the host CD4 T-cell membrane -

prevent the HIV virus envelope from fusing to the host CD4 T-cell membrane -

-Co-receptor antagonists –stabilize the CCR5 co-receptor on CD4 T cells in a conformation which HIV cannot bind to –

- Attachment Inhibitors – novel class of HIV ARTs bind to the gp120 protein on the outer surface of HIV, preventing HIV from binding to and entering CD4 T cells -

ISW: Oncogenic viruses and infections caused by oncogenic viruses.

1. Classification and characteristic features ofoncogenic viruses.

2. Human T-lymphothropic viruses (HTLV-I, HTLV-II). Routs of transmission/ Pathigenesis of leukemia.

3. DNA-containing oncogenic: Papillomaviridae, Polyomaviridae, Adenoviridae, Hepadnaviridae, Herpesviridae, Poxviridae.

4. Family Papillomaviridae. The role of some types in etiology of benign and malignant tumors. Specific prophylaxis of cervical cancer.

5. Oncogens and protooncogenes. Molecular-genetic mechanisms of virus-induced oncogenesis.

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