Protective function of blood. Protective function of saliva. Innate Immunity. Acquired (Adaptive) Immunity. Blood groups system and Rh factor. Hemostasis. (Variable course, VC)

Theme 3. (VC)

Goal of the lesson to study the role of blood in the provision of innate and acquired immunity.

Questions for discussion.

1. Protection of an organism against antigens. Innate immunity, its components.

2. Protection of an organism against antigens. Acquired immunity: cellular and humoral.

3. Blood group system, Rh factor system, determination method, blood transfusion rules.

4. Hemostasis: vascular and platelet function and coagulation, role in dentistry.

Books recommended

1. Ganong W.F. Review of Medical Physiology. 20thed; McGraw-Hill Companies, Inc., 2001. – P.

2. Guyton A.C., Hall J.E. Textbook of Medical Physiology, 12thed; WB Saunders, 2008.

Blood groups were discovered by the Austrian scientist K. Landsteiner and the Czech physician J.Janski in 1901 and 1903.

The group affiliation of blood is determined by the presence of antigens A and B in red blood cells, and in the plasma of antibodies alpha and beta.

the blood of one person, antigens of the same name and antibodies (for example, A and alpha) never occur, if such a meeting occurs, the red cells glue (agglutination) and the person will die.

Practical work 1. Determination of blood groups using serum.

For this work you need:serum anti-A and anti-B, plate, scarifier, alcohol, iodine, cotton wool, glass slide, saline dropper.

Technique: On a plate put two drops of serum, pierced finger, pre-treating it with alcohol, squeeze out a drop of blood on a sterile glass luneckas and area of a glass slide transfer a drop of blood to drop one serum, then another area can also carry a drop of blood to drop another serum. The result is determined after 2 – 3 minutes, if the blood was a lot, you can add a drop of saline solution.

Result: Indicate the presence of agglutination in drops, sketch the result.

Conclusion: to Determine what blood type the test , to explain the mechanism of agglutination.

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