TOPIC: ENDOCRINE SYSTEM. Alloxan destroys Langerhans B cells, causing them not to produce insulin and not lower blood glucose.. See the effect of insulin on the body (Virtual experiments) VIDEO file and fill the table. Results. Write down in a notebook th

TOPIC: ENDOCRINE SYSTEM

Exercise 1. Effect of insulin and alloxan on blood glucose levels

Insulin is a peptide hormone that is produced by the B -cells of the pancreatic islets of Langerhans. Insulin has a variety of effects on metabolism in almost all tissues. The main action of insulin isthe regulation of carbohydrate metabolism, in particular, the utilization of glucose in the body.

Insulin increases the permeability of membranes for glucose so that cells absorb glucose from the blood, and its content there decreases.

Violation of insulin secretion due to destruction of B –cells -Absolute insulin deficiency - is a key link in the pathogenesis of type 1 diabetes. Violation of the action of insulin on tissues - relative insulin deficiency - has an important place in the development of type 2 diabetes.

Alloxan destroys Langerhans B cells, causing them not to produce insulin and not lower blood glucose.

Methodic of this work:

!!! See the effect of insulin on the body (Virtual experiments) VIDEO file and fill the table

1. To determine the content of glucose in the blood of healthy (NORMAL) rat (control experience).

2. Enter alloxan to the rat. To determine the content of glucose in the blood.

3. Enter insulin to the rat. To determine the content of glucose in the blood.

4. Enter alloxan and then insulin to the rat. To determine the content of glucose in the blood.

Results. Write down in a notebook the obtained values of glucose concentration

	1.Normal Rat	2. Alloxan Rat	3. Insulin Rat	4. Alloxan Rat treated by Insulin
Conventional units (mg/dl)
SI Units (mmol/l) Multiple x 0.05

⇐ Предыдущая 123 Следующая ⇒