When should patients seek treatment for gout?

When should patients seek treatment for gout?

Changes in lifestyle, such as limiting foods associated with gout, should be initiated in anyone who has had gouty attacks. Treatment of gout with medications is necessary when frequent disabling gouty attacks occur, when kidney stones caused by uric acid are present, when there is evidence of joint damage from gout on X-rays, or when tophi are present. Treatment should be individualized to the patient.

Do gout medications have any side effects?

Gout medications are well tolerated by most people. However, like other medications, they have potential side effects.
Allopurinol is well tolerated by most people, but in some people, it can cause an allergic rash. Very severe rashes rarely can occur after taking allopurinol, and any allergic type rashes that develop while a patient is taking allopurinol are taken seriously.
Colchicine (Colcrys) can cause signs and symptoms such as nausea, diarrhea, and rarely muscle weakness and abnormal blood counts.
Probenecid is generally well tolerated but should not be used in patients who have uric acid kidney stones, as it can worsen the kidney stones and potentially harm the kidneys in these patients.
Febuxostat (Uloric) can cause liver abnormalities, nausea, and rash.
NSAIDs can cause irritation of the stomach and ulcers in some cases. The liver and the kidneys are periodically monitored in patients taking NSAIDs over the long term.
Krystexxa is administered as an intravenous infusion. Severe allergic reactions have been reported in a minority of people receiving Krystexxa.

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