Individual work. student of _____ group. Lesson 5. ENZYMES: MECHANISM OF ACTION.

Individual work

student of _____ group

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⁽^name⁾

Lesson 5. ENZYMES: MECHANISM OF ACTION.

1. Write Michaelis –Mentene equation:

2. Draw the graph of dependence of enzymatic reaction velocity from substrate concentration, what is K_m (show on graph and write the definition)? Draw the graph of dependence of enzymatic reaction velocity from enzyme concentration.

V		V
	[S]		[Е]

К_m– ________________________________________________________________________

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3. Explain what is “induced fit model” theory?

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4. Name the theories of enzyme action illustrated by this pictures.

A ______________________________ B ______________________________

5. Task: «Why doctor must give oxygen pillow (or oxygen under pressure) for patient with carbon monoxide poisoning but not only carry out him to fresh air?»

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6. Task: «Methanol is very toxic. Why treatment by large doses (100–200 ml) of ethanol is effective during acute poisoning by methanol? »

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7. Fumarase catalyzes conversion of fumarate (trans-isomer) into malate; but doesn’t catalyze conversion of malonate (cis-isomer). What kind of specificity does this enzyme have? _____________________

8. Fill in the scheme.

9. Name the units of enzyme activity and describe each of them.

1. ___________________________________________________________________________

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2. ___________________________________________________________________________

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3. ___________________________________________________________________________

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